Extinction Learning in Adults With Tourette Syndrome

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but are still understudied for individuals with Tourette syndrome (TS). This study examines extinction learning and extinction recall in adults with TS using an experimental task. This study will also explore the relationship between extinction processes (i.e., extinction learning and extinction recall) and treatment outcomes with behavior therapy. Findings from this investigation will be used to update the behavioral treatment model, which serves as the basis for evidence-based behavioral interventions.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: Accepts Healthy Volunteers
View:

• At least 18 years old,

• Have moderate tic severity or greater as evidenced by a YGTSS Total Tic Score greater than 13 (>9 for youth with motor or vocal tics only)

• Have not received more than 4 previous sessions of HRT

• Be fluent in English

• Medication free or on a stable dose of psychiatric medication for 8 weeks prior to enrollment.

Locations
United States
Maryland
Johns Hopkins University School of Medicine
Recruiting
Baltimore
Contact Information
Primary
Nicholas Myers
coach@jhmi.edu
4432877157
Time Frame
Start Date: September 18, 2020
Estimated Completion Date: September 30, 2023
Participants
Target number of participants: 50
Treatments
Experimental: Habit Reversal Training
Habit Reversal Training (HRT) is a multi-component evidence-based treatment for tics. It will be delivered over 8 hours of treatment.
Authors
Joseph F McGuire
Sponsors
Leads: Johns Hopkins University

This content was sourced from clinicaltrials.gov

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