Extinction Learning in Youth With Tourette Syndrome

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but have not been directly evaluated in youth with Tourette syndrome (TS). This study examines extinction learning and extinction recall in youth with TS using an experimental task. This study will also explore the relationship between extinction processes (i.e., extinction learning and extinction recall) and treatment outcomes with behavior therapy. Findings from this investigation will be used to update the behavioral treatment model, which serves as the basis for evidence-based behavioral interventions.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 8
Maximum Age: 17
Healthy Volunteers: Accepts Healthy Volunteers
View:

• age 8-17 years (inclusive)

• have moderate tic severity or greater as evidenced by a YGTSS Total Tic Score greater than 13 (>9 for youth with motor or vocal tics only)

• have not received more than 4 previous sessions of HRT

• be fluent in English.

• Medication free or on a stable dose of psychiatric medication for 8 weeks prior to enrollment.

Locations
United States
Maryland
Johns Hopkins University School of Medicine
Recruiting
Baltimore
Contact Information
Primary
Joey Essoe, PhD
essoe@jhmi.edu
443-287-7157
Backup
Joseph F. McGuire, PhD
jfmcguire@jhmi.edu
443-287-7157
Time Frame
Start Date: February 28, 2019
Estimated Completion Date: July 1, 2023
Participants
Target number of participants: 50
Treatments
Experimental: Habit Reversal Training
Habit Reversal Training (HRT) is a multi-component evidence-based treatment for tics. It will be delivered over 4 two-hour sessions in an intensive format.
Authors
Joseph F McGuire
Sponsors
Leads: Johns Hopkins University

This content was sourced from clinicaltrials.gov

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