Developing a Rapid Objective Functional MRI Assessment and Report to Characterize Functional Abilities and Predict Persistent Symptoms Following Traumatic Brain Injury

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

Our project aims to develop a rapidly acquired and communicated MRI assessment and report that incorporates functional and structural imaging to convey information about functional neurological insults following traumatic brain injury (TBI) that are not typically visible on clinical imaging. Within this framework, there are two sub-studies. The first is a prospective study of patients with TBI who will have an MRI in the sub-acute period after their injury, followed by clinical assessments up to 90 days post-injury. A model will be developed to link MRI biomarkers to persistent symptoms of TBI. The second sub-study will use a focus group methodology to develop the report content and format with input from several groups of stakeholders.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• \- Diagnosis of TBI

• \- Diagnosis of TBI greater than one year prior

• \- Relation who was diagnosed with TBI greater than one year prior that individual was the primary caregiver for

• \- Employment as a physician or allied health professional who has spent greater than 50% of their time treating TBI patients for at least two years of their career

• \- Employment as a personal injury lawyer or insurance adjuster who has spent greater than 50% of their time on TBI cases for at least two years of their career

Locations
Other Locations
Canada
University of Calgary
RECRUITING
Calgary
Queen's University
RECRUITING
Kingston
Contact Information
Primary
Douglas J Cook, MD, PhD
dj.cook@queensu.ca
1-613-549-6666
Backup
Chantel Debert, MD, MSc
cdebert@ucalgary.ca
1-403-944-4224
Time Frame
Start Date: 2024-11
Estimated Completion Date: 2026-06
Participants
Target number of participants: 300
Treatments
TBI patients
Individuals with chronic TBI
Caregivers of individuals with chronic TBI
Clinicians who treat individuals with TBI
Legal and insurance personnel
Related Therapeutic Areas
Sponsors
Leads: D.J Cook
Collaborators: University of Calgary

This content was sourced from clinicaltrials.gov