Efficacy of Azithromycin Plus Doxycycline Compared to Doxycycline Plus Placebo in Patients With Rocky Mountain Spotted Fever in Hospital General de Mexicali of ISESALUD and Hospital General No. 30 Instituto Mexicano Del Seguro Social

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

The aim of this study is to impove the pharmacological treatment of Rocky mountain spotted fever, since is a very ancient disease with an antibiotic therapy that have not changed much the mortality rates, being compared with the natural curse of the disease.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: No
View:

• Any gender

• Over 18 years old

• hospitalized in the internal medicine service, emergency department or intensive care unit of Hospital General de Mexicali (ISESALUD) or Hospital General Zona No. 30 (IMSS) with suspicion of RMSF that present fever and 2 or more of the next symptoms: headache, myalgia, rash, nausea, pharyngeal hyperemia, vomiting, abdominal pain, neurological disorders.

• In addition to at least one of the next epidemiologycal fators: presence of vectors in areas of residence or endemic areas visited two weeks prior to the onset of symptoms, history of visiting or residing in areas with RMSF transmission in the last two weeks, existence of confirmed cases in the locality of origin, history of vector bite or contact with dogs in the two weeks.

Locations
Other Locations
Mexico
Hospital General de Mexicali
Recruiting
Mexicali
Contact Information
Primary
Hiram J. Jaramillo-Ramirez, MD
grupoinvestigacionmedica@gmail.com
686 135 8412
Backup
Gisel V. Licon-Martinez, MD
viviana.licon@uabc.edu.mx
686 194 5903
Time Frame
Start Date: May 12, 2022
Estimated Completion Date: December 31, 2025
Participants
Target number of participants: 86
Treatments
Experimental: A
Azithromycine group
Placebo Comparator: B
Placebo group
Authors
Hiram J Jaramillo-Ramirez
Sponsors
Leads: Hospital General de Mexicali

This content was sourced from clinicaltrials.gov

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