Efficacy of Azithromycin Plus Doxycycline Compared to Doxycycline Plus Placebo in Patients With Rocky Mountain Spotted Fever in Hospital General de Mexicali of ISESALUD and Hospital General No. 30 Instituto Mexicano Del Seguro Social

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3

The aim of this study is to impove the pharmacological treatment of Rocky mountain spotted fever, since is a very ancient disease with an antibiotic therapy that have not changed much the mortality rates, being compared with the natural curse of the disease.

Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: No

• Any gender

• Over 18 years old

• hospitalized in the internal medicine service, emergency department or intensive care unit of Hospital General de Mexicali (ISESALUD) or Hospital General Zona No. 30 (IMSS) with suspicion of RMSF that present fever and 2 or more of the next symptoms: headache, myalgia, rash, nausea, pharyngeal hyperemia, vomiting, abdominal pain, neurological disorders.

• In addition to at least one of the next epidemiologycal fators: presence of vectors in areas of residence or endemic areas visited two weeks prior to the onset of symptoms, history of visiting or residing in areas with RMSF transmission in the last two weeks, existence of confirmed cases in the locality of origin, history of vector bite or contact with dogs in the two weeks.

Other Locations
Hospital General de Mexicali
Contact Information
Hiram J. Jaramillo-Ramirez, MD
686 135 8412
Gisel V. Licon-Martinez, MD
686 194 5903
Time Frame
Start Date: May 12, 2022
Estimated Completion Date: December 31, 2025
Target number of participants: 86
Experimental: A
Azithromycine group
Placebo Comparator: B
Placebo group
Hiram J Jaramillo-Ramirez
Leads: Hospital General de Mexicali

This content was sourced from clinicaltrials.gov

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