Clinical Outcomes of Small Infantile Hemangiomas Treated With Pulsed Dye Laser.

Journal: Dermatologic Surgery : Official Publication For American Society For Dermatologic Surgery [Et Al.]
Treatment Used: Pulsed Dye Laser
Number of Patients: 53
MediFind Summary

Summary: The purpose of the study was to investigate clinical outcomes of pulsed dye laser in small infantile hemangioma lesions.

Conclusion: Even small lesions, especially combined-type, often result in cosmetic problems after pulsed dye laser treatment.


Background: Infantile hemangioma (IH) often causes cosmetic disfigurement. Early intervention with propranolol for large, high-risk lesions is recommended in the American Academy of Pediatrics' Clinical Practice Guideline. Conversely, strategies for the management of small, low-risk lesions have not been established; however, pulsed dye laser (PDL) is often used to treat these lesions.

Objective: To investigate clinical outcomes of PDL in small IH lesions.

Methods: Fifty-three cases with 58 small IHs which did not meet the criteria for high-risk lesions in the guideline and were treated only with PDL were retrospectively reviewed. The characteristics of IHs and residual skin changes after treatment were evaluated.

Results: Forty-seven lesions (81.0%) were superficial hemangiomas, whereas 11 (19.0%) were combined-type. The median maximum diameter was 10.0 mm. Forty-five lesions (77.6%) exhibited various residual skin changes after PDL treatment, including anetoderma (53.5%), telangiectasia and erythema (43.1%), hyperpigmentation (34.5%), redundant skin (3.4%), and fibrofatty tissue (3.4%). Of these, the incidence of anetoderma and fibrofatty tissue were significantly higher in the combined group than in the superficial group ( p = .036 and .033, respectively).

Conclusions: Even small lesions, especially combined-type, often result in cosmetic problems after PDL treatment.

Misako Nakazono, Shintaro Kagimoto, Tomoyuki Koike, Toshihiko Satake, Jiro Maegawa

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