Mediastinal infantile hemangioma with spinal canal extension and extensive gastrointestinal involvement complicated by respiratory failure.

Journal: Pediatric Blood & Cancer
Treatment Used: Diuretic, Vincristine, Corticosteroids, and Propranolol
Number of Patients: 1
Published:
MediFind Summary

Summary: This case report describes an infant with infantile hemangioma with spinal canal extension and gastrointestinal involvement with respiratory failure treated with diuretics, vincristine, corticosteroids, and propranolol.

Conclusion: An infant with infantile hemangioma with spinal canal extension and gastrointestinal involvement with respiratory failure was successfully treated with diuretics, vincristine, corticosteroids, and propranolol.

Abstract

Infantile hemangioma is the most common soft tissue tumor of infancy. Extensive organ involvement is rare. This report describes an infant with biopsy confirmed infantile hemangioma with diffuse organ involvement causing anemia and failure to thrive. Treatment was initiated with propranolol and led to initial improvement; however, course was complicated by several episodes of respiratory failure secondary to pulmonary edema. Propranolol therapy was interrupted for several months while patient was maintained on a diuretic regimen and treated with vincristine and high-dose corticosteroids. Patient was transitioned back to propranolol and is clinically thriving with objective improvement on radiographic imaging.

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