What is the definition of Vasculitis?

Vasculitis is considered to be an autoimmune disease wherein the immune system causes inflammation of the blood vessels. The disease can be acute or chronic. There are many types of vasculitis, which mainly occurs in rare diseases. Vasculitis causes changes in blood vessels which decrease blood flow and oxygen to body tissues and vital organs. While the causes of vasculitis are often unknown, it can occur after an infection, another disease, or a reaction to medication when the immune system is triggered and attacks the vascular system. Genetics may also be a factor.

What are the symptoms for Vasculitis?

Signs and symptoms of vasculitis can vary but include red spots, lumps, or sores on the skin, rash, nerve problems (which may cause numbness or weakness in hands and feet), cough and difficulty breathing, fever, weight loss, and fatigue.

What are the current treatments for Vasculitis?

The treatment depends on the type of vasculitis, with the goal of stopping the inflammation. While some vasculitis may improve without treatment, some types require steroids, immunosuppressive drugs such as cyclophosphamide, methotrexate, azathioprine, newer drugs such as rituximab, or surgery.
  • Condition: Takayasu's Arteritis with Subcutaneous Nodules in a 4-year -old Child
  • Journal: JNMA; journal of the Nepal Medical Association
  • Treatment Used: Oral Corticosteroid and Methotrexate
  • Number of Patients: 1
  • Published —
This case report describes a 4-year-old girl diagnosed with Takayasu arteritis.
  • Condition: IgA Vasculitis with Nephritis in Children
  • Journal: BMC pediatrics
  • Treatment Used: Leflunomide Therapy Combined with Corticosteroid
  • Number of Patients: 5
  • Published —
This case series describes the use of leflunomide therapy for the treatment of IgA vasculitis with nephritis in children.