Summary: There is growing evidence that COVID-19 threatens maternal and perinatal health. Pregnant women are at higher risk of severe complications (severe pneumonia, hospitalizations, intensive care unit admission, invasive mechanical ventilation, extracorporeal membrane oxygenation) and death compared to age-matched non-pregnant women. On the other hand, the number of confirmed COVID-19 cases reported in...
Who is this study for: Child to adult patients with Combined Immunodeficiency
Enrollment Status: Recruiting
Publish Date: October 07, 2021
Intervention Type: Device, Drug, Other
Study Drugs: Anti-thymocyte, Fludarabine
Study Phase: Phase 1/Phase 2
Summary: Infants with severe combined immunodeficiency (SCID) have a profound decrease in number and function of immune cells, and therefore remain highly vulnerable to infection. If not corrected this often leads to death. Hematopoietic cell transplantation (HCT) from matched sibling donor is the standard treatment for these patients, unfortunately though; most SCID patients lack a sibling donor. Building...