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Mark W. Kieran

Dana Farber Cancer Institute
Pediatrics
Male

Bio


Mark Kieran is a Pediatrics specialist in Boston, Massachusetts. He has been an author on 190 peer reviewed articles and participated in 2 clinical trials in the past 15 years. Dr. Kieran's top three areas of expertise are Brain Stem Cancer, Diffuse Intrinsic Pontine Glioma, and Posterior Fossa Tumor. He is licensed to treat patients in MA.

Contact

44 Binney St
Room Sw331
Boston, MA 02115, US

Latest Research


Latest Advance
Study
  • Condition: Pediatric Patients with BRAF V600 Mutation-Positive Relapsed or Refractory Low-Grade Glioma
  • Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
  • Treatment Used: Dabrafenib
  • Number of Patients: 32
  • Published —
This study explored he activity and safety of dabrafenib treatment in patients with BRAF V600 mutation-positive pediatric low-grade glioma (brain tumor; pLGG).
Latest Advance
Study
  • Condition: Recurrent or Refractory BRAF V600 Mutation-Positive Cancer in Children
  • Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
  • Treatment Used: Dabrafenib
  • Number of Patients: 27
  • Published —
This study aimed to determine the safety, tolerability, and activity of dabrafenib in pediatric patients with advanced BRAF V600-mutated cancers.
Latest Advance
Study
  • Condition: Hutchinson-Gilford Progeria Syndrome
  • Journal: Bone
  • Treatment Used: Calcium carbonate
  • Number of Patients: 63
  • Published —
The study researched the outcomes of extraskeletal calcifications in Hutchinson-Gilford Progeria syndrome.
Latest Advance
Study
  • Condition: Aggressive Multivessel Intraluminal Pediatric Pulmonary Vein Stenosis (PVS)
  • Journal: The Journal of pediatrics
  • Treatment Used: Adjunct Targeted Biologic Inhibition Agents
  • Number of Patients: 48
  • Published —
This study describes the 48- and 72-week outcomes among patients receiving imatinib mesylate?with or without?bevacizumab for multivessel intraluminal pulmonary vein stenosis (PVS).

Clinical Trials


Clinical Trial
Drug
  • Status: Recruiting
  • Study Type: Drug
  • Participants: 40
  • Start Date: November 28, 2017
A Phase II Study of Binimetinib in Children and Adults With NF1 Associated Plexiform Neurofibromas (PNOC010)
Clinical Trial
Drug
  • Status: Recruiting
  • Study Type: Drug
  • Participants: 48
  • Start Date: June 2014
A Phase II Study of Cabozantinib (XL184) for Plexiform Neurofibromas in Subjects With Neurofibromatosis Type 1 in Children and Adults

All Publications
View All


Publication
Study
  • Journal: Proceedings of the National Academy of Sciences of the United States of America
  • Published —
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression.
Publication
Study
  • Journal: Pediatric blood & cancer
  • Published —
Pediatric cancer research: Surviving COVID-19.

Contact

44 Binney St
Room Sw331
Boston, MA 02115, US

Credentials

  • Licenses
    Pediatric Hematology-Oncology in MA

Insurance

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