Direct Measurement of Pericoronary Adipocyte Size Gradient as a Parameter of Immunometabolic Changes of Perivascular Adipose Tissue
Status: Recruiting
Intervention Type: Procedure
Study Type: Observational
SUMMARY
Evaluation of pericoronary adipocyte gradient (PCAT) in relationship with local atherosclerotic changes in a patient undergoing heart transplantation.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 90
Healthy Volunteers: f
View:
• Age 30-90 years
• Diagnosis of dilatational or ischemic cardiomyopathy
• Patients undergoing heart transplantation in IKEM
Contact Information
Primary
Ivana K Lesna, MD, PhD., assoc. prof.
ivana.kralova.lesna@ikem.cz
00420236055445
Backup
Peter Ivak, M.D., PhD, assoc. prof.
peter.ivak@ikem.cz
Time Frame
Start Date: 2023-06-01
Estimated Completion Date: 2029-07-01
Participants
Target number of participants: 60
Treatments
patients with advanced heart failure
A group of patients with advanced heart failure were indicated for heart transplanta-tion for either ischemic or dilatational cardiomyopathy. The study group will also in-clude subjects with previously implanted LVAD as a bridge-to-transplant approach. Predictory-related subgroups will be evaluated separately.
Related Therapeutic Areas
Sponsors
Leads: Institute for Clinical and Experimental Medicine