Multicenter Prospective Randomized Controlled Clinical Trial for Comparison Between Laparoscopic and Open Distal Pancreatectomy for Ductal Adenocarcinoma of the Pancreatic Body and Tail
When pancreatic cancer of the body and tail is diagnosed, a distal pancreatectomy is planned. This operation can be performed with open surgery, or with laparoscopic surgery. This study is a multicenter randomized controlled trial to evaluate the operative outcomes and survival of open versus laparoscopic distal pancreatectomy for pancreatic cancer of the body and tail.
• Eastern Cooperative Oncology Group (ECOG) performance score 0-2
• Pancreatic ductal adenocarcinoma that is pathologically confirmed or shows characteristic radiologic features
• Patients with resectable pancreatic cancer at the time of surgery (Including borderline resectable pancreatic cancer at the time of diagnosis or Locally advanced pancreatic cancer after chemotherapy or radiation therapy)
• Lesion (within pancreatic body and tail) is located to the left of the left branch of the hepatic portal vein
• No remote metastasis in preoperative imaging and not adjacent to the superior mesenteric vein, superior mesenteric artery, and abdominal artery
• Patients without invasion of adjacent organs other than the left adrenal gland and mesocolon
• Patients with informed consent