To Develop and Implement a Method for Optimizing the Volume of Lymph Node Dissection in Radical Surgical Treatment of Localized or Locally Advanced Prostate Cancer
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This is a randomized controlled study assessing outcome of low (no or limited) versus high (limited or extended) extent of lymph node dissection in addition to radical prostatectomy in patients with operable localized or locally advanced prostate cancer.
Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Healthy Volunteers: f
View:
• Age over 18 years.
• Histologically confirmed localized or locally advanced prostate cancer (adenocarcinoma without a neuroendocrine component).
• No evidence of metastatic spread of the tumor
• Local resectability of the tumor according to digital rectal examination and/or CT and/or MRI of the pelvis
• Patients are suitable for radical prostatectomy based on their comorbidities and life expectancy.
• Signed informed consent to participate in the study.
Locations
Other Locations
Belarus
N.N. Alexandrov National Cancer Centre
RECRUITING
Lyasny
Time Frame
Start Date: 2025-10-29
Estimated Completion Date: 2032-05-30
Participants
Target number of participants: 800
Treatments
Experimental: no / limited lymph node dissection
Experimental: limited / extended lymph node dissection
Related Therapeutic Areas
Sponsors
Leads: N.N. Alexandrov National Cancer Centre