Determining the Necessity for Postoperative Antibiotics After Salivary Stent Placement

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

Salivary duct stent placement is a common practice to maintain duct patency after salivary duct repair or interventional sialoendoscopy; procedures performed to manage salivary duct pathology such as stenosis, traumatic injury or most commonly salivary duct stones. It is common practice for patients to receive perioperative antibiotics while undergoing interventional sialoendoscopy and postoperative oral antibiotic therapy with Clindamycin or Augmentin for 10-14 days, if a short term (2 week) salivary duct stenting was considered necessary due to the nature of the intervention. However, In reviewing the literature, there are controversial trials that indicate post-operative antibiotics may not be best practice in all surgical scenarios, as the adverse events ie. gastrointestinal disturbances, nausea, Clostridium difficile (C.diff) infection and antibiotic resistance over time surrounding overuse of antibiotics may outweigh the clinical need for the antibiotic regiment and the chances of post-operative infection.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• All adult patients (18 years of age or older) who are undergoing salivary duct surgery and stent placement at Our Lady of the Lake Regional Medical Center

Locations
United States
Louisiana
Our Lady of the Lake Regional Medical Center
RECRUITING
Baton Rouge
Contact Information
Primary
Rohan Walvekar, M.D.
rwalve@lsuhsc.edu
225-765-1765
Backup
Leslie Son, Ph.D.
lson@lsuhsc.edu
225-757-4165
Time Frame
Start Date: 2018-06-15
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 40
Treatments
Active_comparator: Group A (Antibiotic)
Group A will receive postoperative oral antibiotics for 10 - 14 days (Clindamycin or Augmentin) upon discharge.
No_intervention: Group B (no Antibiotic)
Group B will not be given postoperative oral antibiotics upon discharge.
Related Therapeutic Areas
Sponsors
Leads: Our Lady of the Lake Hospital
Collaborators: Louisiana State University Health Sciences Center in New Orleans

This content was sourced from clinicaltrials.gov