SAS 1: Develop Ocular Disease (OSD) Diagnostic, Algorithms, and Management Protocols for Cataract Surgery
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Patient: Tear film issues resulting in poor visual outcomes are a major cause of dissatisfaction after cataract surgery. There is no universal best preoperative algorithm for managing the ocular surface prior to surgery. Industry: Recent advances in tear/cornea imaging and refractive cataract surgery such as multifocal intraocular lenses will be advantageous to patients only if tear film issues can be addressed. Society: Cataract surgery is the most common ophthalmic surgery done in Singapore and worldwide. Improving vision by attending to tear film problems improves quality of life.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 99
Healthy Volunteers: t
View:
• Inclusion criteria for dry eye (participant must meet at least 1 of the inclusion criteria below):
∙ Symptomatic for dry eye based on DEQ5 (\>6) and \[either TBUT less than 5 s or staining \>grade 1 in any zone of the cornea\]
‣ Either use of diquasfosol, cyclosporine eyedrops or tacrolimus eyedrops for dry eye disease in the last 2 weeks (and previously started for more than 2 months), OR current and visible lower punctal plugs in at least one eye
⁃ DEQ5 \<=6.
⁃ Staining \< grade 1 in at least one corneal zone.
⁃ Not using diquasfosol, cyclosporine, tacrolimus in last 2 months.
⁃ No visible punctal plugs.
Locations
Other Locations
Singapore
Singapore Eye Research Institute
RECRUITING
Singapore
Contact Information
Primary
Louis Tong, PhD
louis.tong.h.t@singhealth.com.sg
65767200
Backup
Lee Jia Yi, MSc
lee.jiayi1@singhealth.com.sg
65767200
Time Frame
Start Date:2025-06-27
Estimated Completion Date:2027-10-31
Participants
Target number of participants:110
Treatments
Post LVC with Dry Eye undergoing cataract surgery
Post LVC with Dry Eye undergoing cataract surgery
High corneal Astigmatism with Dry Eye undergoing cataract surgery
High corneal Astigmatism with Dry Eye undergoing cataract surgery
Dry eye with no other risk factor undergoing cataract surgery
Dry eye with no other risk factor undergoing cataract surgery
Patient undergoing Cataract Surgery implanted with EDoF/ EDoF Toric IOL With Dry Eye
Patient undergoing Cataract Surgery implanted with EDoF/ EDoF Toric IOL With Dry Eye
Patient undergoing Cataract Surgery implanted with Multifocal/ MultifocalToric IOL With Dry Eye
Patient undergoing Cataract Surgery implanted with Multifocal/ MultifocalToric IOL With Dry Eye
Patient undergoing Cataract Surgery implanted with Toric IOL With Dry Eye
Patient undergoing Cataract Surgery implanted with Toric IOL With Dry Eye
Patient undergoing Cataract Surgery implanted with Monofocal IOL With Dry Eye
Patient undergoing Cataract Surgery implanted with Monofocal IOL With Dry Eye
Patient undergoing Cataract Surgery implanted with EDoF/ EDoF Toric IOL Without Dry Eye
Patient undergoing Cataract Surgery implanted with EDoF/ EDoF Toric IOL Without Dry Eye
Patient undergoing Cataract Surgery implanted with Multifocal/ MultifocalToric IOL Without Dry Eye
Patient undergoing Cataract Surgery implanted with Multifocal/ MultifocalToric IOL Without Dry Eye
Patient undergoing Cataract Surgery implanted with Toric IOL Without Dry Eye
Patient undergoing Cataract Surgery implanted with Toric IOL Without Dry Eye
Patient undergoing Cataract Surgery implanted with Monofocal IOL Without Dry Eye
Patient undergoing Cataract Surgery implanted with Monofocal IOL Without Dry Eye