Efficacy of Remifentanil in Preventing Emergence Agitation in Patients Undergoing Nasal Surgery Under Desflurane Anesthesia: A Prospective Double-blind Randomized Controlled Trial.
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The primary aim of the study was to test the hypothesis that remifentanil administered for analgesia prevents emergence agitation more effectively than fentanyl and N2O in patients undergoing rhinoplasty who received desflurane as an inhaled anesthetic agent. The secondary aim of the study was to compare the demographic data, intraoperative and postoperative hemodynamic data, surgical time and modified Aldrete score of patients who received different intraoperative analgesia methods.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: t
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• The study included patients over the age of 18, planned to undergo rhinoplasty by the plastic and reconstructive surgery department, and American Society of Anesthesiologist (ASA) I-II.
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Locations
Other Locations
Turkey
Health Sciences University Gazi Yaşargil Training and Research Hospital
RECRUITING
Diyarbakır
Contact Information
Primary
Hülya Tosun Söner
hulyatosunsoner@hotmail.com
+905352792102
Backup
Osman Uzundere
osmanuzundere@gmail.com
+905330206362
Time Frame
Start Date: 2024-08-01
Estimated Completion Date: 2024-10-01
Participants
Target number of participants: 99
Treatments
Active_comparator: group 1 Remifentanily
Patients in Group 1 received 0.05-0.2 μg/kg/min IV remifentanil infusion as analgesic.
Active_comparator: group 2 N2O
N2O instead of 50% air was applied to patients in Group 2 for intraoperative analgesia.
Active_comparator: group 3 Fentanly
In addition to Desflurane, 50% oxygen and 50% air, 1 μg/kg IV fentanyl bolus was administered as analgesic when there was a 20% increase in heart rate and blood pressure values during the operation for patients in Group 3.
Related Therapeutic Areas
Sponsors
Leads: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital