Effectiveness of Single Bolus Versus Continuous Infusion of Dexmedetomidine in Mitigating Agitation in Adults Undergoing Nasal Surgery: a Prospective Randomized Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The main objective of study is to compare dexmedetomidine single bolus dose before extubation with continuous infusion as regards their efficacy in mitigating the incidence of emergence agitation in obese adults undergoing nasal surgery.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: t
View:
• American Society of Anesthesiologist (ASA) Ⅰ or II
• Adults with body mass index (BMI) \< 30 Kg/m
• Underwent elective nasal surgery.
Locations
Other Locations
Egypt
Fayoum University Hospital
RECRUITING
Al Fayyum
Contact Information
Primary
Yasser S Mostafa, MD
ysm03@fayoum.edu.eg
01010509735
Backup
Mohamed A Shawky, MD
mas14@fayoum.edu.eg
0 109 525 4547
Time Frame
Start Date: 2025-03-01
Estimated Completion Date: 2025-10-01
Participants
Target number of participants: 50
Treatments
Experimental: Bolus group
single dose 0.5 µg/kg in 15 ml saline over 10 min , started 15 minutes before end of surgery
Experimental: Infusion group
Infusion of dexmedetomidine at a dose of 0.5 µg/kg/h without loading dose all through intraoperative time
Related Therapeutic Areas
Sponsors
Leads: Fayoum University Hospital