Changes in Perfusion Index Under Low-Flow Anesthesia and Its Effects on Postoperative Emergence in Pediatric Patients

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to evaluate changes in perfusion index (PI) in pediatric patients undergoing elective surgery under low-flow anesthesia. PI will be monitored at multiple intraoperative and postoperative time points to assess its relationship with hemodynamic stability and depth of anesthesia. The study will also investigate whether low-flow anesthesia affects the incidence of emergence agitation (EA). Patients will be assigned to either low-flow or normal-flow anesthesia groups based on routine clinical practice. No intervention will be applied beyond standard care. The findings are expected to provide insight into the predictive value of PI in postoperative recovery and support safer anesthesia practices in pediatric populations.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 2
Maximum Age: 12
Healthy Volunteers: f
View:

• ASA I-II pediatric patients

• Age 2 to 12 years

• Undergoing elective surgery lasting between 1-6 hours

• Informed consent obtained from parents/guardians

Locations
Other Locations
Turkey
Istinye Üniversity
RECRUITING
Istanbul
Contact Information
Primary
ilke dolgun
ilkeser2004@gmail.com
+905555485632
Time Frame
Start Date: 2025-06-15
Estimated Completion Date: 2025-08-10
Participants
Target number of participants: 90
Treatments
Experimental: Low-Flow Anesthesia Group (LFA)
Patients will receive general anesthesia using a fresh gas flow rate of 1 L/min (50% O₂ + 50% air). Perfusion index and hemodynamic parameters will be monitored at predetermined time points.
Active_comparator: Normal-Flow Anesthesia Group (HFA)
Patients will receive general anesthesia using a fresh gas flow rate of 2 L/min (50% O₂ + 50% air). Perfusion index and hemodynamic parameters will be monitored at the same time points.
Related Therapeutic Areas
Sponsors
Leads: Istinye University

This content was sourced from clinicaltrials.gov