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Delirium in Neurodegenerative Disease Patients: A Music Therapy Intervention for Hospital Care

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

In this pilot study a new kind of music therapy will be created and tested to help prevent confusion, called delirium, that can happen in the hospital. This can affect people with brain diseases like Alzheimer's disease and Parkinson's disease. Each of the anticipated 30 participants will have up to five music therapy sessions. The sessions will be made just for them and may include live music, playing instruments, or listening to recorded music. Surveys will be used to learn how easy the therapy is to do in the hospital and what people think about how helpful the sessions may be for future patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:

• Admitted as inpatient to Boston Medical Center.

• Cognitive impairment or neurodegenerative diseases as defined by either:

‣ Diagnosis of Parkinson's Disease, Dementia with Lewy Bodies (ICD-10 G20 and G31.83 respectively), Alzheimer's Disease-related dementias (ICD-10 6D80), vascular dementia (F01), or other cognitive impairment (R41) on active problem list or past medical history

⁃ Cognitive impairment on active problem list or past medical history

⁃ Documentation elsewhere in the electronic medical record (e.g. notes) of any of these conditions

• Participants with cognitive impairment will be included. If unable to consent, legally authorized representative (LAR) based on HRP-013-SOP-LARs, Children, and Guardians will be contacted to consent.

• Spanish speaking participants will be included. Screening and informed consent procedures will be conducted using a certified medical interpreter. All intervention sessions and study team interactions will be conducted using these interpreter services.

• Patients admitted to an intensive care unit will be included as long as they are not receiving continuous intravenous sedative medications. Potential participants in the intensive care unit setting will be discussed with a PI/co-I to ensure participation is appropriate on a case-by-case basis. The PI/Co-I will confirm with the treating physician that there are no reasons as to why the potential participant should not be enrolled in the study.

Locations
United States
Massachusetts
Boston Medical Center
RECRUITING
Boston
Contact Information
Primary
Kara M Smith, MD MSCI FAAN
kara.smith@bmc.org
617-638-5351
Backup
Amber Payne, MS
amber.payne@bmc.org
Time Frame
Start Date: 2026-03-11
Estimated Completion Date: 2026-12
Participants
Target number of participants: 30
Treatments
Experimental: Music therapy
Participants will undergo one-on-one music therapy (MT) sessions of approximately 30 minutes duration conducted by a board-certified music therapist. Sessions will be customized to address patient needs but will consistently adhere to the four principal MT methods of re-creation, composition, improvisation, and therapeutic listening experiences.
Related Therapeutic Areas
Sponsors
Leads: Boston Medical Center

This content was sourced from clinicaltrials.gov

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