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The Role of Heart Rate Variability and Anxiety in Predicting Emergence Agitation in Patients Undergoing Septorhinoplasty : A Prospective Observational Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This prospective observational study aims to evaluate whether preoperative heart rate variability (HRV) and anxiety are associated with, and can help predict, emergence agitation in adult patients undergoing elective septorhinoplasty under general anesthesia. Preoperative anxiety will be assessed using a visual analog scale (VAS) and the State-Trait Anxiety Inventory (STAI-1). Resting HRV will be recorded preoperatively using a chest-strap heart rate monitor and HRV metrics (e.g., SDNN, RMSSD, LF/HF) will be derived. Emergence agitation will be assessed in the post-anesthesia care unit (PACU) using the Richmond Agitation-Sedation Scale (RASS) during the early recovery period. Secondary observations will include early postoperative events such as postoperative nausea and vomiting (PONV) and laryngospasm. The study is planned to enroll approximately 100 participants.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Age 18 to 65 years

• ASA physical status I-II

• Scheduled for elective septorhinoplasty under general anesthesia

• Able to provide informed consent and complete questionnaires

Locations
Other Locations
Turkey
Konya City Hospital
RECRUITING
Konya
Contact Information
Primary
Mahmut TUTAR, MD
masatu42@gmail.com
+905552723704
Time Frame
Start Date: 2026-02-01
Estimated Completion Date: 2026-08-01
Participants
Target number of participants: 100
Treatments
Emergence Agitation
Participants who exhibit emergence agitation during early recovery in the PACU, defined as a Richmond Agitation-Sedation Scale (RASS) score ≥ +1 within the first 30 minutes after arrival to the PACU.
No Emergence Agitation
Participants who do not exhibit emergence agitation during early recovery in the PACU, defined as RASS \< +1 throughout the first 30 minutes after arrival to the PACU.
Related Therapeutic Areas
Sponsors
Leads: Konya City Hospital

This content was sourced from clinicaltrials.gov