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Association Between Cerebral Oxygen Consumption Responsiveness to Increased Oxygen Supply and Postoperative Delirium: A Prospective Observational Study Using Functional Near-Infrared Spectroscopy

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

The goal of this observational study is to learn whether the brain's ability to use oxygen during surgery is associated with postoperative delirium in adults aged 65 years and older undergoing general anesthesia. The main question it aims to answer is: \- Does reduced cerebral oxygen consumption responsiveness during surgery increase the risk of postoperative delirium in older patients? Participants who are undergoing elective laparoscopic surgery under general anesthesia as part of their routine medical care will have brain oxygen levels measured during surgery using a non-invasive forehead sensor, and will be assessed for delirium for up to three days after surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 65
View:

• Patients undergoing elective laparoscopic surgery under general anesthesia

• Age 65 years or older

Locations
Other Locations
Republic of Korea
Seoul National University Bundang Hospital
RECRUITING
Seongnam-si
Contact Information
Primary
Soowon Lee, MD, PhD
soowonlee@snubh.org
+82-31-787-7499
Time Frame
Start Date: 2026-03-11
Estimated Completion Date: 2028-05
Participants
Target number of participants: 80
Treatments
Older patients undergoing elective laparoscopic surgery
Adults aged 65 years and older undergoing elective laparoscopic surgery under general anesthesia will be prospectively observed. During surgery, cerebral oxygen levels will be measured using a non-invasive forehead sensor to assess the brain's oxygen utilization response within the range of routine anesthesia care. Participants will be followed for up to three days after surgery to evaluate the occurrence of postoperative delirium.
Related Therapeutic Areas
Sponsors
Leads: Seoul National University Bundang Hospital

This content was sourced from clinicaltrials.gov