Use of Fibroblast Activation Protein Inhibitor (FAPI) PET-CT Before Surgery in Patient with Endometriosis
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Patients with suspected endometriosis scheduled for surgery will be identified. They will be asked to participate in a study evaluating the feasibility of FAPI PET-CT in diagnosing endometriosis. The results will be compared with surgical findings, pathology, and other imaging techniques if available (i.e., MRI, US).
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:
• Female participants aged 18-45 years
• Clinical suspicion of endometriosis based on symptoms
• Scheduled for diagnostic/therapeutic laparoscopic surgery
• Ability to understand and provide written informed consent
• Completed and signed Radiation Exposure Documentation Form
Locations
Other Locations
Israel
Ziv Medical Center
RECRUITING
Safed
Contact Information
Primary
Israel Sandler, MD
israels@ziv.gov.il
+972-527-362280
Time Frame
Start Date: 2025-03
Estimated Completion Date: 2027-06
Participants
Target number of participants: 30
Treatments
Experimental: FAPI PET-CT Diagnostic Arm
Participants undergo FAPI PET-CT imaging at multiple timepoints (10, 30, 60, and 80 minutes post-injection) using a single FAPI dose. Each participant will then undergo laparoscopic surgery with tissue sampling for pathological confirmation of endometriotic lesions.
Related Therapeutic Areas
Sponsors
Leads: Ziv Hospital