Endometriosis Clinical Trials

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Predicting the Efficacy of Dienogest in Patients With Endometriosis Using MRI

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this prospective observational study is to learn whether magnetic resonance imaging (MRI) findings can help predict treatment response to dienogest in women with endometriosis. Endometriosis is a common gynecologic condition that can cause chronic pelvic pain and negatively affect quality of life. Although dienogest is widely used as a standard medical treatment, individual responses to treatment vary. The main questions this study aims to answer are: * Whether baseline MRI characteristics of endometriotic lesions are associated with improvement in pelvic pain after dienogest treatment. * Whether MRI findings can help identify patients who are more likely to benefit from dienogest therapy. Participants diagnosed with endometriosis who are prescribed dienogest as part of their routine clinical care will be enrolled. This study does not assign any investigational intervention. Participants will undergo standard clinical follow-up, including pelvic pain assessment using visual analog scale (VAS) scores, quality of life questionnaires, and routine MRI examinations. Clinical and imaging data will be collected prospectively and analyzed to explore imaging predictors of treatment response.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 19
Maximum Age: 45
Healthy Volunteers: f
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• Female participants who have received a full explanation of the study and have provided written informed consent

• Women aged 19 to 45 years who have been diagnosed with endometriosis by a board-certified obstetrician-gynecologist

• Patients who have not received any hormonal treatment within the previous 3 months

• Patients who have never been treated with dienogest

Locations
Other Locations
Republic of Korea
Sejong Chungnam National University Hospital
RECRUITING
Sejong
Time Frame
Start Date: 2025-10-14
Estimated Completion Date: 2027-03
Participants
Target number of participants: 48
Related Therapeutic Areas
Sponsors
Leads: Chungnam National University Sejong Hospital

This content was sourced from clinicaltrials.gov