Fertility Preservation in Case of Endometriosis : Observational Cohort Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Fertility Preservation is now considered as crucial for the well-being of women battling cancer. However, others indications have more recently emerged. Women with endometriosis may represent a suitable group since they are at risk for compromise ovarian reserve. Data on FP in endometriosis patients are rare: only small retrospective study, case-reports and opinion publications .Nowadays, there is no available data concerning real indications for PF on endometriosis patients (endometriomas, risk of surgery, deep endometriosis?), criteria for eligibility (ovarian reserve parameters, age), quality of oocytes and number of oocytes necessary to give at least one live birth. We propose a monocentric observational cohort study, evaluating the efficacy of oocytes cryopreservation as fertility preservation procedure, in young adult female subjects with endometriosis, to finally define the criteria of eligibility for PF procedures in case of endometriosis.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 36
Healthy Volunteers: f
View:

• women from 18 to 36 years old

• endometriosis disease proved by sonography, MRI and/or surgery

• Consenting to participate to the study

Locations
Other Locations
France
Service de Gynécologie Obstétrique et Médecine de la Reproduction Hôpital TENON
RECRUITING
Paris
Contact Information
Primary
Emmanuelle Mathieu d'Argent, MD
emmanuelle.mathieu@aphp.fr
+33 156 01 68 69
Backup
Emile Darai, MD, PhD
emile.darai@tnn.aphp.fr
Time Frame
Start Date: 2018-12-04
Estimated Completion Date: 2025-12
Participants
Target number of participants: 100
Treatments
Women with endometriosis
Women with endometriosis disease aged 18-36 years, with appropriate endometriosis diagnosis, based on transvaginal sonography, magnetic resonance imaging and/or previous surgery.Ovarian reserve was assessed by antral follicle counting (AFC) and measurement of serum anti-Mullerian hormone (AMH) levels Enrolled after preservation fertility procedure (vitrification of mature oocytes)
Related Therapeutic Areas
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov