ProspeCtive Observational Real-world Study of uBRogepant and Atogepant in Israel (COBRA)

Status: Recruiting
Location: See all (11) locations...
Study Type: Observational
SUMMARY

Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will evaluate how effective the use of ubrogepant and atogepant is in treating adult participants with migraine. Urogepant (Ubrelvy) and Atogepant (Qulipta) are approved drugs for treatment of migraine in adults in the US. Approximately 200 adult participants who are prescribed Ubrogepant or atogepant by their doctors will be enrolled in this study in Israel. Participants will receive ubrogepant oral tablets or atogepant oral tablets as prescribed by their physician. Participants will be followed for 90 days. There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Confirmed diagnosis of migraine according to the ICHD-3 upon judgement of the treating physician

• The patients should be naive to the designated treatment

• Ability to fill an e-diary app

Locations
Other Locations
Israel
Assuta Ashdod Medical Center /ID# 260020
RECRUITING
Ashdod
Soroka University Medical Center /ID# 254551
COMPLETED
Beersheba
Clalit HMO /ID# 257364
RECRUITING
Gani Tikva
Edith Wolfson Medical Center /ID# 269740
RECRUITING
Holon
Hadassah Medical Center-Hebrew University /ID# 257352
RECRUITING
Jerusalem
Shaare Zedek Medical Center /ID# 254169
RECRUITING
Jerusalem
Maccabi Healthcare Services /ID# 254171
RECRUITING
Kfar Saba
Meir Medical Center /ID# 254170
RECRUITING
Kfar Saba
The Chaim Sheba Medical Center /ID# 254550
RECRUITING
Ramat Gan
ZIV Medical Center /ID# 257360
RECRUITING
Safed
Tel Aviv Sourasky Medical Center /ID# 263089
RECRUITING
Tel Aviv
Contact Information
Primary
Tal Nevo
tal.nevo@abbvie.com
+972(0)97909600
Time Frame
Start Date: 2023-06-25
Estimated Completion Date: 2025-09
Participants
Target number of participants: 200
Treatments
Ubrogepant
Participants will receive ubrogepant as prescribed by their physician in routine clinical practice.
Atogepant
Participants will receive atogepant as prescribed by their physician in routine clinical practice.
Related Therapeutic Areas
Sponsors
Leads: AbbVie

This content was sourced from clinicaltrials.gov