A Prospective, Single-Arm Study of a Modified Lumbar Puncture (LP) Procedure That Reduces Post-Lumbar Puncture Headaches (PLPH) in Adult Patients
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this study is to o determine whether the modified LP procedure reduces the incidence of PLPH to 5% or lower, to determine whether the modified LP procedure reduces the frequency of epidural blood patch (EBP) usage to 10% or lower of the PLPH population and to identify factors that may contribute to or reduce incidence of PLPH
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Participants who can sign informed consent
• Participants who have stated willingness to comply with all study procedures and availability for the duration of the study
• Participants receiving a LP per standard of care (SOC) need for diagnostic or therapeutic purposes only
• Participants with Karnofsky Performance Scale (KPS) ≥ 60
Locations
United States
Texas
The University of Texas Health Science Center at Houston
RECRUITING
Houston
Contact Information
Primary
Jay-Jiguang Zhu, MD,PhD
Jay.Jiguang.Zhu@uth.tmc.edu
(713) 486-8000
Backup
Austin Lu
Austin.Lu@uth.tmc.edu
(713) 486-7758
Time Frame
Start Date: 2023-11-08
Estimated Completion Date: 2026-04-01
Participants
Target number of participants: 100
Treatments
Experimental: Modified Lumbar Puncture
Related Therapeutic Areas
Sponsors
Leads: The University of Texas Health Science Center, Houston