BActeriophages To Treat Liver Disease Eliminating Harmful Bacteria (BATTLE)
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
Alcoholic hepatitis is a disease with a high mortality rate with few treatment options improving survival. Recently certain bacterial strains has been correlated to survival in patients with alcoholic hepatitis. In the BATTLE-trial the investigators will investigate if certain bacteria are correlated to decreased chance of survival in patients with alcoholic hepatitis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥ 18
• Bilirubin \> 50 micromol/L
• History of large alcoholic consumption in period prior to hospital admission (in the last six months)
• No bile-duct obstruction (investigated through US, CT og MRI)
Locations
Other Locations
Denmark
Copenhagen University Hospital Hvidovre
RECRUITING
Hvidovre
Contact Information
Primary
frederik cold, MD, PHD
frederik.cold@regionh.dk
+4521157167
Time Frame
Start Date: 2022-07-01
Estimated Completion Date: 2026-01-01
Participants
Target number of participants: 30
Treatments
Hospital admitted patients with alcoholic hepatitis
Inclusion criteria:~Age ≥ 18 Bilirubin \> 50 micromol/L History of large alcoholic consumption in period prior to hospital admission (in the last six months) No bile-duct obstruction (investigated through US, CT og MRI)~Exclusion criteria:~Hepatocellulary carcinoma Viral hepatitis Autoimmune hepatitis Portal thrombosis Pregnancy Expected survival for less than one year caused by other diseases (based on decision from project responsible doctors)
Related Therapeutic Areas
Sponsors
Leads: Copenhagen University Hospital, Hvidovre
Collaborators: Copenhagen University Hospital at Herlev