Is Negativity of Autoantibodies a Marker of Severity in Auto-immune Hepatitis

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

Evaluate the proportion of seronegative auto-immune hepatitis and a possible relationship with the severity of the disease. Criteria of severity will be defined by corticodependance, corticoresistance and a severe form of the disease at diagnosis (cirrhosis or fulminant hepatitis). In case of predominant seronegative forms, other auto-antibodies related to this auto-immue hepatitis will be searched.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• \- Any patient over 18 years old

• Patient followed at Hôpital Saint-Antoine or treated for HAI or in Guadeloupe within the framework of the CCRD Filfoie for an acute or chronic AIH under immunosuppressive treatment

• Patient affiliate or beneficiary of a social security scheme

• Free, informed and written consent signed by the patient and the investigator

Locations
Other Locations
France
Hospital of Saint-Antoine
NOT_YET_RECRUITING
Paris
CHU de Pointe-à Pitre
RECRUITING
Pointe À Pitre
Contact Information
Primary
Valérie SOTER, Promotion Unit manager
valerie.soter@chu-guadeloupe.fr
+590 590 934677
Backup
Eunice NUBRET, Project manager
eunice.nubret@chu-guadeloupe.fr
+590 0590934686
Time Frame
Start Date: 2022-07-01
Estimated Completion Date: 2026-12
Participants
Target number of participants: 100
Treatments
acute or chronic Auto-Immune Hepatitis patients
For the study, a blood sample will be collected from the patient in order to build up a serological library which allow the search for rare autoAb whose interest has been demonstrated as prognostic factors of the disease
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Universitaire de la Guadeloupe

This content was sourced from clinicaltrials.gov