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Effect of Postoperative Ozonated Oil Dressing on Early Wound Inflammation After Open Mesh Inguinal Hernia Repair: A Prospective Randomized Pilot Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Other, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study looks at whether a special wound dressing containing ozonated oil can reduce early wound inflammation after open inguinal hernia surgery. Open inguinal hernia repair is a common operation, and although infection rates are low, many patients experience redness, swelling, tenderness, or discomfort at the surgical site during the first days after surgery. Participants undergoing elective open inguinal hernia repair will be randomly assigned to receive either an ozonated oil-impregnated dressing or a standard sterile dressing after the operation. The main outcome is the level of wound inflammation measured on the third day after surgery. Other outcomes include wound temperature, pain levels, cosmetic healing, and wound-related problems during the first 30 days. The ozonated oil used in this study is a CE-certified medical product that is already used in routine wound care. This pilot study aims to provide preliminary data to help determine whether ozonated oil dressing may improve early wound healing compared with standard care.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Adults aged 18 to 75 years

• ASA physical status I-III

• Scheduled for elective, unilateral open inguinal hernia repair

• Able to provide written informed consent

Locations
Other Locations
Turkey
Dr. Ali Rıza Erdoğan Private Practice Office
RECRUITING
Niğde
Contact Information
Primary
Ali Rıza Erdoğan, Medical doctor
dralirizaerdogan@gmail.com
+905333558377
Time Frame
Start Date: 2026-02-10
Estimated Completion Date: 2026-05-31
Participants
Target number of participants: 60
Treatments
Experimental: Ozonated Oil Dressing
Participants receive a sterile gauze dressing impregnated with CE-certified ozonated oil applied to the surgical incision after skin closure. The dressing is changed once daily for the first 48 hours, followed by standard wound care.
Active_comparator: Standard Sterile Dressing
Participants receive a standard sterile dry dressing applied to the surgical incision after skin closure. The dressing is removed within 24-48 hours postoperatively, and subsequent wound care is continued according to routine institutional practice.
Related Therapeutic Areas
Sponsors
Leads: Nigde Omer Halisdemir University

This content was sourced from clinicaltrials.gov