• 1\. Male or postmenopausal female participants, aged 18 years or older, with a confirmed diagnosis of SHPT.

• 2\. The BMI is between 18 kg/m2 and 35 kg/m2;

• 3\. The subjects must undergo regular maintenance hemodialysis three times a week for at least three months；

• 4\. Within 14 days prior to randomization, subjects must have serum calcium levels≥ 8.4 mg/dL;

• 5.Subject capable of understanding written information ,willing to participate in, and provide a written informed consent;