Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1
SUMMARY
The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 3
Healthy Volunteers: t
View:
⁃ Healthy Volunteers:
• Subject has no diagnosed pulmonary conditions
• Ability to read and understand English or Spanish
⁃ Subjects with Lung Disease:
• Subject has a diagnosis of pulmonary dysfunction made by a physician
• No acute worsening of pulmonary function in the past 30 days
• Ability to read and understand English or Spanish
Locations
United States
Kansas
University of Kansas Medical Center
RECRUITING
Kansas City
Contact Information
Primary
Cristal Monge
chernandez@kumc.edu
913-945-9399
Time Frame
Start Date: 2020-11-02
Estimated Completion Date: 2026-10-26
Participants
Target number of participants: 260
Treatments
Experimental: Hyperpolarized 129Xe
Administration of hyperpolarized xenon during MRI (up to 1L doses) to develop imaging methods and assess pulmonary function in adults.
Related Therapeutic Areas
Sponsors
Leads: Mario Castro, MD, MPH