An Open-Label, Superiority, Randomized, Comparative Study to Evaluate the Efficacy and Safety of Telmisartan, Amlodipine, and Chlorthalidone Fixed-Dose Combination Versus Telmisartan, Amlodipine, and Hydrochlorothiazide in Elderly Patients with Essential Hypertension Uncontrolled by Telmisartan and Amlodipine Combinations

Status: Recruiting
Location: See all (15) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

This study is to compare the efficacy and safety of Telmisartan, Amlodipine, and Chlorthalidone Fixed-Dose Combination and Telmisartan, Amlodipine, and Hydrochlorothiazide in Elderly Patients with Essential Hypertension Uncontrolled by Telmisartan and Amlodipine Combinations

Eligibility
Participation Requirements
Sex: All
Minimum Age: 65
Healthy Volunteers: f
View:

• Participants who have been fully informed about the purpose, content, and characteristics of investigational product, and have voluntarily agreed in writing

• Aged ≥ 65 with essential hypertension

• Patient with uncontrolled essential hypertension at screening

‣ If already taking antihypertensive drugs, mean sitting systolic blood pressure (MSSBP) must be 140 mmHg ≤ MSSBP \< 200 mmHg

⁃ If not taking any antihypertensive drugs at least 4 weeks, mean sitting systolic blood pressure (MSSBP) must be 160 mmHg ≤ MSSBP \< 200 mmHg

Locations
Other Locations
Republic of Korea
Pusan National University Yangsan Hospital
RECRUITING
Busan
The Catholic University of Korea Daejeon ST. Mary's Hospital
RECRUITING
Daejeon
Wonju Severance Christian Hospital
NOT_YET_RECRUITING
Gangwon-do
Chonnam National University Hospital
RECRUITING
Gwangju
Gwangju Veterans Hospital
RECRUITING
Gwangju
The Catholic University of Korea, ST. Vincent's Hospital
RECRUITING
Gyeonggi-do
he Catholic University of Korea, Incheon ST. Mary's Hospital
RECRUITING
Incheon
Hanyang university medical center
NOT_YET_RECRUITING
Seoul
Korea University Guro Hospital
RECRUITING
Seoul
Seoul national University Budang hospital
RECRUITING
Seoul
The Catholic University of Korea Bucheon St.Mary's Hospital
RECRUITING
Seoul
The Catholic University of Korea, Eunpyeong St. Mary's Hospital
RECRUITING
Seoul
The Catholic University of Korea, Seoul ST. Mary's Hospital
RECRUITING
Seoul
The Catholic University of Korea, Uijeongbu ST. Mary's Hospital
RECRUITING
Seoul
The Catholic University of Korea, Yeouido ST. Mary's Hospital
RECRUITING
Seoul
Contact Information
Primary
Minjun Kim
clinicaltrials@yuhan.co.kr
+82-2-828-0508
Backup
bokyung Lee
bklee@yuhan.co.kr
+82-2-828-0778
Time Frame
Start Date: 2023-10-18
Estimated Completion Date: 2025-10-28
Participants
Target number of participants: 250
Treatments
Experimental: Telmisartan/Amlodipine/Chlorthalidonea 40/5/12.5 mg
Telmisartan/Amlodipine/Chlorthalidonea 40/5/12.5 mg will be orally administered during the study period
Active_comparator: Telmisartan/Amlodipine/Hydrochlorothiazide 40/5/25 mg
Telmisartan/Amlodipine 40/5 mg and Hydrochlorothiazide 25 mg will be orally administered each during study period
Related Therapeutic Areas
Sponsors
Leads: Yuhan Corporation

This content was sourced from clinicaltrials.gov

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