Dose Response Study of the Effects of a Daily Supplementation With a Black Garlic Extract, ABG+/GarlACE on Cardiovascular Disease Risk Factors in Subjects With Grade I Hypertension
Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this clinical trial is to evaluate the dose response effect on cardiovascular disease risk factors of a Black Garlic Extract in subjects with Grade I Hypertension. The main questions it aims to answer are: * If the reduction in blood pressure (systolic and diastolic) is in a dose-response manner * If the changes in lipid profile are in a dose-response manner Participants will be randomly assign to a low dose (250 mg/day), high dose (600 mg/day) or placebo of a standardized Garlic Extract (ABG+/GarlACE) during 12 weeks
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: t
View:
• Men and women with Grade I Hypertension (systolic blood pressure between 130 and 139 mmHg; and diastolic blood pressure between 80 to 89 mmHg) without taking any antihypertensive drug
Locations
Other Locations
Spain
University of Lleida
RECRUITING
Lleida
Time Frame
Start Date: 2024-02-26
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 180
Treatments
Experimental: Low Dose
250 mg/day of Garlic Extract
Experimental: High Dose
600 mg/day of Garlic Extract
Placebo_comparator: Placebo
Placebo tablets
Related Therapeutic Areas
Sponsors
Collaborators: Pharmactive Biotech Products S.L.U
Leads: Universitat de Lleida