Exercise Performance on Ambient Air vs. Commonly Prescribed Nasal Low Oxygen Therapy - a Non-inferiority Trial in Patients With Exercise Induced Desaturation Due to Pulmonary Vascular Disease (PVD)
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The investigators aim to study the effect of SOT in Swiss residents with pulmonary vascular diseases (PVD) defined as pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Minimum 18 years of age
• Written informed consent
• Patients with diagnosed pulmonary arterial hypertension (PAH), distal chronic thromboembolic pulmonary hypertension (CTEPH)
• Former desaturation under exercise defined as Spo2-decrease \>3%
• Treated with a stable drug therapy (with no changes for at least 14 days prior to screening)
Locations
Other Locations
Switzerland
University Hospital Zürich
RECRUITING
Zurich
Contact Information
Primary
Silvia Ulrich, Prof. Dr.
silvia.ulrich@usz.ch
+41442552220
Backup
Mona Lichtblau, Dr.
mona.lichtblau@usz.ch
+41442552220
Time Frame
Start Date: 2024-04-01
Estimated Completion Date: 2025-12
Participants
Target number of participants: 28
Treatments
Experimental: Ambient air
Patient will perform tests at University Hospital Zurich
Active_comparator: SOT via basal canula
Supplemental Oxygen Therapy (SOT) at approximately 3l/min will be provided via nasal canula from a small oxygen concentrator while the patient performs tests at University Hospital Zurich.
Related Therapeutic Areas
Sponsors
Leads: University of Zurich