Evaluation and Exploration of the Safety and Efficacy of Superselective Adrenal Arterial Embolization in Patients With Essential Refractory Hypertension: A Proof-of-Concept Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The subjects of this study were patients with essential refractory hypertension. The purpose of this study is to evaluate the safety and efficacy of superselective adrenal arterial embolization (SAAE) in patients with primary refractory hypertension and to explore the possibility of SAAE in patients with primary refractory hypertension.After the subject completes the SAAE, an 8-week follow-up will be conducted to assess the safety and effectiveness of the SAAE.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age \> 18 years, no gender restrictions;

• Primary refractory hypertension: Taking three antihypertensive drugs, including a - diuretic, with an average office systolic blood pressure ≥150 mmHg measured three times;

• Duration of hypertension greater than 6 months;

• Standing plasma aldosterone and renin activity not below the lower limit of the unit's reference range;

• Signed informed consent form.

Locations
Other Locations
China
The Second Affiliated Hospital of Nanchang University
RECRUITING
Nanchang
Contact Information
Primary
Yifei the second affiliated hospital of Nanchang university, Doctor
yf_dong66@126.com
(0791)86209562
Time Frame
Start Date: 2024-08-01
Estimated Completion Date: 2027-12
Participants
Target number of participants: 20
Treatments
Experimental: Interventional treatment group
superselective adrenal arterial embolization
Related Therapeutic Areas
Sponsors
Leads: Second Affiliated Hospital of Nanchang University

This content was sourced from clinicaltrials.gov