MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors
Inflammation and stressors can interfere with the function of the lining of blood vessels and insulin activity, therefore, investigators are aiming to see how the Grape seed Extract (GSE) called MegaNatural BP can help with limiting the effects of these factors. This research will study the effects of taking 150mg of MegaNatural BP GSE per day on blood pressure levels along with influences on heart health through assessing the function of the blood vessel lining and levels of inflammation.
• 40-60 years of age
• BMI \< 30kg/m2
• elevated blood pressure 120-140 mmHg (systolic) / \<90 mmHg (diastolic) at screening visit
• Has fasting blood glucose concentration between 100-125 mg/dL or HbA1c 5.7-6.4%.
• Not taking any medications that would interfere with outcomes of the study, i.e. blood pressure lowering medications or anti-diabetes medications.
• Able to provide informed consent
• Able to comply and perform the procedures requested by the protocol (including dietary restrictions, consumption of study foods, records of food diary and GI tolerance questionnaire, sample collection procedures and study visit schedule)
• Able to maintain usual physical activity pattern
• Able to avoid / abstain from alcohol and vigorous physical activity for 24 hours prior to and during study visit