Effect of Heated Water-Based Versus Land-Based Exercise Training on Hemodynamic Variables, Functional Capacity and Quality of Life in Older

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

BACKGROUND: Physical exercise promotion is one of the main global goals of innumerous health and medical societies for preventing and managing noncommunicable chronic diseases (NCDs), being one of the main therapeutic for the patient with hypertension. Exercise in heated swimming pool has emerged as a potential alternative to physical exercise on the ground for the reduction of blood pressure (BP) of hypertensive patients, however, its effects on BP, as well as hemodynamic, metabolic, inflammatory and functional variables of older individuals with hypertension have not been investigated. PURPOSE: To evaluate the effects of heated water-based exercise (HEx) versus land-based exercise (LEx) on BP, arterial stiffness, endothelial function, metabolic, inflammatory and functional variables of older individuals with hypertension. METHODS: 60 older individuals (male and female) with hypertension (age \> 60 years) will be randomized in 2:2:1 ratio to HEx, LEx or control (CON) intervention. The feasibility and physiological adaptations (physical capacity, musculoskeletal and cardiovascular responses to stress, biological and biochemical markers associated with the pathophysiology of the disease and vascular adaptations) will be assessed before, after 12 weeks and after 24 weeks of follow-up. HEx and LEx training programs will be performed three times per week and will be performed for the firs 12 weeks of follow-up.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:

⁃ \- For the study population, the following will not be included in the study:

• Smokers (avoiding acute effects of smoking on physiological measures);

• Individuals with decompensated cardiovascular disease, thyroid dysfunction and / or inflammatory diseases;

• Unable individuals to perform an exercise program or ergospirometric test due to physical or mental incapacity;

• Individuals with hemodynamic and / or electrocardiographic changes during the ergospirometric test.

• Only individuals older than 60 years, with a diagnosis of SAH for more than 6 months (stage 1 or 2), using antihypertensive medication (office BP less than 140/90 mmHg) and without medication change for at least 2 months.

Locations
Other Locations
Brazil
Universidade Estadual Paulista Julio de Mesquita Filho
RECRUITING
Bauru
Contact Information
Primary
Awassi Y. Ngomane, Master
awassiyn@gmail.com
+5511985678113
Time Frame
Start Date: 2025-09-01
Estimated Completion Date: 2027-08-30
Participants
Target number of participants: 60
Treatments
Experimental: HAS HEX vs HAS LEX
Experimental: HAS HEX vs HAS CON
Experimental: HAS LEX vs HAS CON
Related Therapeutic Areas
Sponsors
Collaborators: Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Leads: Universidade Estadual Paulista Júlio de Mesquita Filho

This content was sourced from clinicaltrials.gov