AXILL-ART: Lymphedema Evaluation After Adjuvant Hypofractionated Radiotherapy for 1-2 Macrometastatic Sentinel Lymph Nodes Without Axillary Dissection in Breast Cancer Conservative Surgery: Observational Study
Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Observational
SUMMARY
In this observational prospective studi patients with invasive breast cancer no more than 5 cm and clinically node negative, scheduled for conservative surgery and Sentinel Node Biopsy (SNB), are enrolled in the protocol if they have 1-2 sentinel lymphnodes (SLNs) with macrometastases. SLN status will be checked on definitive sections.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Histological proven invasive breast cancer
• Breast conserving surgery with no axillary dissection
• Tumor dimension no more then 5 cm and no more than 2 positive sentinel node
⁃ 5\) Negative surgical margin (no tumor cell on ink) 6) Performance Status (PS) \<2 7) Age \>18 8) Written informed consent
Locations
Other Locations
Italy
European Institute of Oncology
RECRUITING
Milan
Contact Information
Primary
Maria Cristina Leonardi, MD
cristina.leonardi@ieo.it
+39 02 94372156
Time Frame
Start Date: 2019-04-18
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 120
Treatments
Hypofractionated radiotherapy
Hypofractionated radiotherapy scheme with 2.67Gy/fraction for 15 fractions. WBRT with simultaneous integrated boost to the tumor bed
Related Therapeutic Areas
Sponsors
Leads: European Institute of Oncology