The Role of Melatonin as an Adjuvant Therapy in Childhood Pneumonia
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY
The goal of this study is to compare the mean length of hospital stay between children with pneumonia receiving melatonin as an adjuvant therapy and those receiving standard of care alone. The hypothesis is that combining oral melatonin with standard treatment can reduce the length of hospital stay as compared to standard of care alone. The control group will receive standard treatment (antibiotic) while the intervention group will receive standard treatment plus melatonin for 14 days.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 1 month
Maximum Age: 12
Healthy Volunteers: f
View:
• 1 month to 12 years
• Both genders
• Patient diagnosed as having pneumonia or severe pneumonia according to WHO definition
Locations
Other Locations
Pakistan
Pakistan Institute of Medical Sciences
RECRUITING
Islamabad
Time Frame
Start Date: 2025-05
Estimated Completion Date: 2026-01
Participants
Target number of participants: 60
Treatments
No_intervention: Standard Treatment
Standard treatment - Antibiotic such as ampicillin in a dose of 50mg//kg/dose x TDS
Experimental: Adjuvant Therapy
Standard Treatment along with Melatonin @ 1 mg/dose in infants and 2.5 to 3mg/dose in children three times a day for 14 days
Related Therapeutic Areas
Sponsors
Leads: Mian Muhammad Hassan Ahmed