Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired Pneumonia Treated With Beta-lactams
Status: Recruiting
Location: See all (5) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The purpose of this study is to compare effectiveness and safety of Azithromycin versus Doxycycline in adult patients hospitalized with community acquired pneumonia (CAP) treated with Beta-lactams.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• • All adult patients (\>18 years old) admitted with CAP and receiving a beta-lactam antibiotic plus a form of atypical coverage (azithromycin or doxycycline) in the ED within 12 hours of admission.
Locations
United States
Arizona
Mayo Clinic in Arizona
NOT_YET_RECRUITING
Scottsdale
Florida
Mayo Clinic in Florida
NOT_YET_RECRUITING
Jacksonville
Minnesota
Mayo Clinic Health System-Mankato
NOT_YET_RECRUITING
Mankato
Mayo Clinic in Rochester
RECRUITING
Rochester
Wisconsin
Mayo Clinic Health System-La Crosse
NOT_YET_RECRUITING
La Crosse
Time Frame
Start Date: 2025-09-15
Estimated Completion Date: 2031-09-01
Participants
Target number of participants: 1120
Treatments
Active_comparator: Doxycycline group
Subjects hospitalized for community acquired pneumonia will receive standard of care treatment with Doxycycline
Active_comparator: Azithromycin group
Subjects hospitalized for community acquired pneumonia will receive standard of care treatment with Azithromycin
Related Therapeutic Areas
Sponsors
Leads: Mayo Clinic