Corneal and Tear Film Changes in Chinese Patients With Type 2 Diabetes: a Cross-sectional Controlled Study
Status: Unknown
Location: See location...
Study Type: Observational
SUMMARY
Diabetes mellitus has been associated with ocular surface damage and exacerbates dry eye disease (DED) pathology. To investigate clinical and inflammatory changes in the ocular surface of insulin-independent type II diabetic patients. This cross-sectional control study will recruit 200 Type 2 diabetic patients and 200 age- and sex-matched subjects without DM.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: f
View:
• Participants are diagnosed with dry eye according to the TFOS DEWS II diagnostic criteria: (a) OSDI questionnaire ≥13, (b) Non-invasive tear breakup time (NITBUT) \<10 s, (c) ocular surface staining \>5 corneal spots, greater than nine conjunctival spots (The presence of two or more criteria was used to establish a positive DE diagnosis).
• Age ≥ 18
Locations
Other Locations
China
He Eye Hospital
RECRUITING
Shenyang
Contact Information
Primary
Guanghao Qin
qinguanghao@hsyk.com.cn
+8618842664420
Time Frame
Start Date: 2023-12-30
Completion Date: 2024-12-31
Participants
Target number of participants: 80
Treatments
Study group
Type 2 diabetic patients
Control group
Age- and sex-matched subjects without DM
Related Therapeutic Areas
Sponsors
Leads: He Eye Hospital