Effect of Betamethasone Phonophoresis in Treatment of Vitiligo

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Vitiligo is a skin disorder that results in the formation of depigmented patches or hypopigmented macules due to selective destruction or reduction of melanocytes the cells that produce pigment in our skin. Vitiligo affects 0.1-2% of the World's population. People of all skin types and all ages can be affecte. In most of the cases, white patches develop or expand slowly overtime, and in some cases it never progress and remains stable . Vitiligo can be segmental or non-segmental depending upon the morphology of the clinical involvement. It can also be classified as stable or unstable based on the activity of disease. Steroids act as anti-inflammatory and immunosuppressant agents. Even if different classes of steroids are now available, the mid- potent ones (e.g. betamethasone dipropionate 0.05% cream, 0.05% clobetasol propionate ointment) are usually preferred for the treatment of young patients . Now days, topical corticosteroids are the most commonly prescribed agents in treatment of dermatologic conditions .Almost all treatments of vitiligo have borrowed from therapies whose prime targets have been another disease.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 25
Maximum Age: 40
Healthy Volunteers: f
View:

• Male and female patients diagnosed with vitiligo.

• Medically and psychologically stable patients.

• Good cognitive abilities to understand the requirements of the study.

• All patients enrolled to the study will have their informed consent.

• they had no contraindications to the use of therapeutic ultrasound

Locations
Other Locations
Egypt
Cairo University Hospital
RECRUITING
Cairo
Contact Information
Primary
Ola Sabry Abd-Elmaksoud Tarabya, MSc
Olasabry17@yahoo.com
+201024035447
Backup
Nisreen Afify Abd-Elrasheed, Professor
Nessrien.afify@pt.cu.edu.eg
+201143872680
Time Frame
Start Date: 2025-11-10
Estimated Completion Date: 2026-02-10
Participants
Target number of participants: 60
Treatments
Active_comparator: Patients Group
This group of patients composed of 30 Male and female patients who received betamethasone cream then after 20 minutes ultrasound was applied, three times per week for 1 month.
Active_comparator: Control Group
This group of patients composed of 30 Male and female patients who received ultrasound then after 20 minutes patients received betamethasone cream, three times per week for 1 month.
Related Therapeutic Areas
Sponsors
Leads: Cairo University

This content was sourced from clinicaltrials.gov