Optimizing Rehabilitation After Achilles Tendon Rupture Repair: The Role of Blood Flow Restriction Training in Tendon and Muscle Recovery

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to investigate whether rehabilitation with blood flow restriction (BFR) offers added value compared to conventional rehabilitation in patients undergoing surgical repair for Achilles tendon rupture. The study will include adult patients of all sexes who have undergone surgical treatment at two selected hospitals. The main questions it aims to answer are: Does BFR-enhanced rehabilitation improve functional recovery compared to conventional rehabilitation? What are the effects of BFR on muscle strength and tendon recovery? Researchers will compare blood flow restriction (BFR) therapy with conventional rehabilitation to determine whether BFR leads to improved clinical, muscular, and tendon-related outcomes. Participants will: 1. Undergo standard surgical repair of the Achilles tendon 2. Be randomly assigned to a 24-week exercise therapy program-either with or without blood flow restriction (BFR)-starting four weeks post-surgery 3. Take part in follow-up assessments at weeks 4, 8, 12, 18, 24, and 52, which will include: * Questionnaires on pain, quality of life, fear of movement, and return to sport * Medical imaging techniques such as ultrasound, MRI, shear wave elastography, and power Doppler * Muscle strength testing * Blood sample collection, along with a tendon tissue sample taken during surgery

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• patients with total midrupture Achilles tendon rupture

• surgical treatment

• \> 18 years old

• able to understand and speak Dutch

Locations
Other Locations
Belgium
Ghent University
NOT_YET_RECRUITING
Ghent
Ghent University Hospital
RECRUITING
Ghent
Contact Information
Primary
Sarah VanDen Berghe
sarah.vandenberghe@ugent.be
+32471178728
Time Frame
Start Date: 2025-08-20
Estimated Completion Date: 2028-11
Participants
Target number of participants: 82
Treatments
Active_comparator: Conventional therapy
control group: patients in this group will undergo the same standard strength training program as the BFR-group, but without a tourniquet.
Experimental: Blood flow restriction group
patients in this group will undergo a standard strength training program combined with an occlusion cuff. The cuff will be used during exercises targeting quadriceps and calf muscles.
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Ghent

This content was sourced from clinicaltrials.gov