Factors Affecting Medication Adherence to Topical Acne Medications: a Single-center, Prospective Study Evaluating the Adherence and Patient Satisfaction to Single and Multiple Topical Acne Medications

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY

Acne is a chronic condition that typically requires the use of multiple medications.1 Medication adherence is especially challenging for patients with chronic diseases and often decreases over time, especially for those using topical medications.1 Nonadherence can result in multiple negative effects including treatment failure, increased healthcare costs, and decreased quality of life. Primary nonadherence refers to problems acquiring and starting treatment. Challenges to this form of nonadherence include a lack of knowledge, misunderstanding of usage, poor communication with provider, increased cost, and fear of side effects.2 Secondary nonadherence refers to when the patient does not use the medication as prescribed. Hurdles to secondary nonadherence include delayed results, increased complexity of treatment plan, adverse effects, busy lifestyle, and inconvenience.2

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• Adult patients ≥18 years of age

• Patients with a current diagnosis of acne

• Patients who live in the US,

• Patients have sufficient command of the English language

Locations
United States
North Carolina
Wake Forest University Health Sciences
RECRUITING
Winston-salem
Contact Information
Primary
Irma M Richardson, MHA
irichard@wakehealth.edu
336-716-2903
Time Frame
Start Date: 2024-02-15
Estimated Completion Date: 2026-11
Participants
Target number of participants: 72
Treatments
Experimental: One gel treatment
Every participant will be instructed to apply a topical retinoid every day.
Experimental: Two gel treatment
One-third of the participants will be instructed to apply adapalene and the clindamycin phosphate/benzoyl peroxide gel every day.
Experimental: Three gel treatment
One-third of the participants will be instructed to apply adapalene, benzoyl peroxide gel, and clindamycin phosphate gel every day.
Related Therapeutic Areas
Sponsors
Collaborators: Bausch Health Americas, Inc.
Leads: Wake Forest University Health Sciences

This content was sourced from clinicaltrials.gov