A Multicenter, Randomized, Double-Blind, Vehicle-Controlled Clinical Study to Evaluate the Efficacy and Safety of Clascoterone Cream 1% in Treatment of Subjects With Facial Acne Vulgaris

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

The primary objective of this study is to determine the safety and efficacy of clascoterone cream, 1%, versus the vehicle cream applied twice daily for 12 weeks in subjects with facial acne vulgaris.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 12
Healthy Volunteers: f
View:

• Diagnosed with facial acne vulgaris (which includes the nose) from moderate to severe, has an Investigator's Global Assessment (IGA) score of 3 or 4; with at least 30 to a maximum of 75 inflammatory lesions (papules, pustules, and nodules) and 30 to a maximum of 100 non-inflammatory lesions (open and closed comedones);

• Male or female, 12 years of age or older;

• Subjects aged 18 years or older are required to provide informed consent and sign the written informed consent. A subject under 18 years of age must provide written informed assent and be accompanied by the parent or legal guardian at the time of consent signing.

Locations
Other Locations
China
Huashan Hospital, Fudan University
RECRUITING
Shanghai
Time Frame
Start Date: 2024-05-20
Estimated Completion Date: 2026-10
Participants
Target number of participants: 692
Treatments
Experimental: Clascoterone Cream 1%
Clascoterone Cream 1% (Winlevi)
Placebo_comparator: Vehicle cream
Vehicle cream manufactured to mimic look and feel of Clascoterone Cream 1% but without the active ingredient.
Related Therapeutic Areas
Sponsors
Leads: Zhejiang Sunshine Mandi Pharmaceutical Co.,Ltd.

This content was sourced from clinicaltrials.gov