Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery
Who is this study for? Patients after third molar surgery
What treatments are being studied? Melatonin
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY
The purpose of the study is to assess if melatonin given for three nights before wisdom tooth surgery decreases post-operative pain and pain medication consumption. Patients will receive either melatonin or a placebo for three nights prior to surgery and we will measure pre-operative anxiety, preoperative sleep quality, post op pain medication consumption, post op pain scores, and blood values.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 35
Healthy Volunteers: t
View:
• Subject must have 3-4 partial or full bony impacted third molars requiring surgical extraction under IV sedation
• Ages 18-35
• ASA Class I or II
• English or Spanish speaking patients
• Capacity to sign informed consent
Locations
United States
New York
Montefiore Medical Center Department of Dentistry
RECRUITING
The Bronx
Contact Information
Primary
Charles K Levin, DDS
montefioreomfs@gmail.com
718-904-8190
Time Frame
Start Date: 2021-05-12
Estimated Completion Date: 2026-12
Participants
Target number of participants: 60
Treatments
Experimental: Experimental Treatment - Melatonin
Premedication for three nights with 10mg melatonin
Placebo_comparator: Control Treatment - Lactose
Premedication for three nights with lactose capsules
Related Therapeutic Areas
Sponsors
Leads: Montefiore Medical Center
Collaborators: Eurofins Viracor, Quest Diagnostics-Nichols Insitute