Intrathecal Morphine for Postoperative Analgesia in Video-Assisted and Robotic-Assisted Thoracic Surgery: A Randomized, Placebo-controlled, Double-blinded Clinical Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug, Other
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
VATS/RATS is widely used for diagnosis and treatment of intrathoracic conditions. Despite many benefits, postoperative pain continues to be intense after VATS/RATS. The optimal strategy for pain management has not been defined. In this randomized, placebo-controlled, double-blinded clinical investigation, investigators hypothesize that 5 mcg/kg intrathecal morphine will decrease postoperative analgesic consumption and reduce pain.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Age 18-80 years old
• Undergoing elective video-assisted thoracoscopic or robotic assisted surgery for anatomical lung resection
• General anesthesia with anticipated intraoperative extubation.
Locations
United States
Illinois
University of Chicago
RECRUITING
Chicago
Contact Information
Primary
Richa Dhawan, MD MPH
richa.dhawan@northwestern.edu
312-695-0061
Time Frame
Start Date: 2023-09-29
Estimated Completion Date: 2026-09-01
Participants
Target number of participants: 90
Treatments
Placebo_comparator: Placebo
Placebo, Intrathecal saline
Active_comparator: Morphine
Intrathecal morphine
Related Therapeutic Areas
Sponsors
Leads: Northwestern University