ENDOblock: Do Bilateral Superficial Cervical Blocks With Local Wound Infiltration Decrease Postoperative Pain After Thyroid Surgery

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This is a single center, prospective, double-blinded randomized controlled trial comparing the efficacy of bilateral superficial cervical plexus blocks (BSCPB) with local wound infiltration vs placebo with local wound infiltration in reducing thyroid surgery postoperative pain. Primary outcomes assessed are post operative pain, quality of life/recovery, post operative nausea/vomiting and opioid use.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: t
View:

• undergoing thyroid surgery, either hemi- or total thyroidectomy

• over 18 years-old and

• able to consent for themselves

Locations
United States
California
UC Davis Medical Center
RECRUITING
Sacramento
Contact Information
Primary
Alexis L Woods, MD
alwoods@ucdavis.edu
2794657077
Backup
Claire E Graves, MD
cegraves@ucdavis.edu
9167345907
Time Frame
Start Date: 2023-04-17
Estimated Completion Date: 2025-11
Participants
Target number of participants: 74
Treatments
Experimental: Bilateral superficial cervical plexus blocks + local wound infiltration
the bilateral superficial cervical plexus block will be performed with 10mL of 0.25% Bupivacaine injected bilaterally (total 20mL) at Erb's point in the lateral neck, which is located at the mid-point between the mastoid process and the posterior border of the clavicular head of the sternocleidomastoid muscle. The injection is just below the lateral border of the sternocleidomastoid muscle, which produces surface level anesthesia of the neck, targeting superficial nerves of the cervical plexus. Then 10mL of 0.25% Bupivacaine will be injected at the planned neck incision (local wound infiltration) on the anterior neck. These will be done intra-operative and only once
Placebo_comparator: placebo + local wound infiltration
10mL of 0.25% bupivacaine injected at the planned neck incision (local wound infiltration), with 10mL of normal saline injected at bilateral Erb's point (total 20mL) (placebo at site of BSCPB). These will be done intra-operative and only once.
Related Therapeutic Areas
Sponsors
Leads: University of California, Davis

This content was sourced from clinicaltrials.gov