Wound Infiltration With Dexmedetomidine in Cesarean Section: Effect on Postoperative Analgesia
Status: Recruiting
Location: See location...
Intervention Type: Drug, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The effects of four different wound infiltration protocols in cesarean section will be investigated on parturient' pain intensity, PCA morphine consumption given, side effects and parturient' overall satisfaction. One group will receive for wound infiltration dexmedetomidine, the second ropivacaine, the third dexmedetomidine combined with ropivacaine, while the last one will receive normal saline (placebo group).
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 40
Healthy Volunteers: f
View:
• pregnancy \>37 weeks, ASA I-II, BMI\<35
Locations
Other Locations
Greece
Paraskevi K Matsota
RECRUITING
Athens
Time Frame
Start Date: 2019-08-23
Estimated Completion Date: 2026-11-20
Participants
Target number of participants: 100
Treatments
Active_comparator: Dexmedetomidine
Drug: dexmedetomidine (Dexmed) 20 mL solution of dexmedetomidine used for wound infiltration
Active_comparator: Ropivacaine
Drug: ropivacaine 20 mL solution of ropivacaine 0.375% used for wound infiltration
Active_comparator: Dexmedetomidine - Ropivacaine
Drug: dexmedetomidine (Dexmed) combined with Drug: ropivacaine 20 mL solution of dexmedetomidine 1γ/kg within ropivacaine 0.375% used for wound infiltration
Placebo_comparator: 0.9 % saline
Drug:0.9 % saline solution (Normal saline). 20 ml with 0.9 % saline solution used for wound infiltration
Related Therapeutic Areas
Sponsors
Leads: Attikon Hospital