Quadratus Lumborum Block to Improve Postoperative Pain Management After Laparoscopic Myomectomies: a Double-blinded and Prospective Randomized Clinical Trial.

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

This study aims to determine the efficacy of a quadratus lumborum (QL) block in decreasing postoperative pain in patients undergoing myomectomy for uterine fibroids. A QL block is a temporary anesthetic injection in the quadratus lumborum muscle, a muscle in the lower back, that has been previously shown to significantly reduce postoperative pain levels in patients undergoing abdominal and pelvic surgery. Because of its demonstrated effects, the QL block is becoming a standard of anesthesia and surgical care. Since participants will be undergoing a myomectomy procedure, the investigators believe that participants may qualify to participate in this study. The investigators will be comparing patients who receive the QL block (in addition to standard anesthesia and postoperative pain care) with patients who do not receive the QL block (in addition to standard care). The participants will be randomly assigned to one of the two groups and may or may not actually receive the block.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:

• Presence of uterine fibroids requiring surgical excision with preservation of the uterus

• Stated willingness to comply with all study procedures and availability for the duration of the study

• Provision of signed and dated informed consent form

Locations
United States
Ohio
University Hospitals Ahuja Medical Center
RECRUITING
Beachwood
Contact Information
Primary
Catherine P Haering, BA
cph43@case.edu
3392011531
Time Frame
Start Date: 2024-08-24
Estimated Completion Date: 2026-07-03
Participants
Target number of participants: 80
Treatments
Experimental: QL Block with Bupivacaine
Participants will get a QL block using 30cc Bupivacaine bilaterally in quadratus lumborum muscle (60cc total).
Sham_comparator: Control
Participants will get a sham injection of 30cc saline bilaterally in quadratus lumborum muscle (60cc total).
Related Therapeutic Areas
Sponsors
Leads: Joseph Findley MD

This content was sourced from clinicaltrials.gov