Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This interventional study aims to test gait biomechanics in healthy individuals with and without experimental muscle pain in the lower extremities. The study aims to: A) Examine how experimental muscle pain in different types of muscles (ankle plantar-flexion, knee extension, and flexion muscles) affects kinematics, kinetics, and muscle activation Participants will receive six muscle injections: a) Hypertonic saline (painful condition) and b) Isotonic saline (control condition) in 1) m. gastrocnemius, 2) m. semitendinosus, and 3) m. biceps femoris.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: t
View:
• Healthy men and women aged 18-45 years
Locations
Other Locations
Denmark
Aalborg University
RECRUITING
Aalborg
Contact Information
Primary
Kristian KS Petersen
kkp@hst.aau.dk
31697510
Backup
Emma Hertel
eh@hst.aau.dk
60887473
Time Frame
Start Date: 2023-11-08
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 36
Treatments
Experimental: Gastrocnemius (painful condition)
1.5 mL injection of hypertonic saline (7%) to the gastrocnemius muscle.
Sham_comparator: Gastrocnemius (control condition)
1.5 mL injection of isotonic saline (0.9%) to the gastrocnemius muscle.
Experimental: Biceps femoris (painful condition)
1.2 mL injection of hypertonic saline (7%) to the biceps femoris muscle.
Sham_comparator: Biceps femoris (control condition)
1.2 mL injection of isotonic saline (0.9%) to the biceps femoris muscle.
Experimental: Semitendinosus (painful condition)
1.2 mL injection of hypertonic saline (7%) to the semitendinosus muscle.
Sham_comparator: Semitendinosus (control condition)
1.2 mL injection of isotonic saline (7%) to the semitendinosus muscle.
Related Therapeutic Areas
Sponsors
Leads: Kristian Kjær Petersen